1-[2-(TrifluoroMethy
1-[[2-(trifluoromethyl)phenyl]methyl]piperazine
CAS: 94022-97-6
Molecular Formula: C12H15F3N2
1-[2-(TrifluoroMethy - Names and Identifiers
| Name | 1-[[2-(trifluoromethyl)phenyl]methyl]piperazine |
| Synonyms | 1-[2-(TrifluoroMethy 1-(2-Trifluoromethyl-benzyl)piperazine 1-[2-(TRIFLUOROMETHYL)BENZYL]PIPERAZINE 1-(2-TrifluoroMethylbenzyl)piperazine 2HCl 1-[[2-(trifluoromethyl)phenyl]methyl]piperazine 1-(2-Trifluoromethylbenzyl)piperazine dihydrochloride |
| CAS | 94022-97-6 |
| EINECS | 301-592-6 |
| InChI | InChI=1/C12H15F3N2/c13-12(14,15)11-4-2-1-3-10(11)9-17-7-5-16-6-8-17/h1-4,16H,5-9H2 |
1-[2-(TrifluoroMethy - Physico-chemical Properties
| Molecular Formula | C12H15F3N2 |
| Molar Mass | 244.26 |
| Density | 1.189g/cm3 |
| Boling Point | 274.1°C at 760 mmHg |
| Flash Point | 107.2°C |
| Vapor Presure | 0.0055mmHg at 25°C |
| Refractive Index | 1.491 |
1-[2-(TrifluoroMethy - Introduction
1-[[2-(trifluoromethyl)phenyl]methyl]piperazine is an organic compound with the chemical formula C16H18F3N3. It is a white crystalline solid, soluble in some polar organic solvents, such as dichloromethane and ethanol, and insoluble in water.
1-[[2-(trifluoromethyl)phenyl]methyl]piperazine has a wide range of applications in the field of medicine. It can be used as a raw material for antidepressants, antipsychotics and anxiolytics. It has also been used in research as an agonist of serotonin and dopamine receptors.
1-[[2-(trifluoromethyl)phenyl]methyl]piperazine has many preparation methods. A common method of preparation is by reacting piperazine with 2-bromobenzonitrile and then with trifluoromethylbenzyl bromide in the presence of sodium bicarbonate to give the desired product.
Regarding safety information, 1-[[2-(trifluoromethyl)phenyl]methyl]piperazine is a chemical and requires caution. It may have irritating and corrosive effects on the eyes, skin and respiratory tract. Pay attention to personal protective measures, such as wearing protective glasses, gloves and protective mask. At the same time, contact with the skin and inhalation of its dust or vapor should be avoided. In case of accidental contact, flush with water immediately and seek medical help. In addition, it is also an environmental pollutant and should be avoided to cause pollution to the environment. In the use and storage, should comply with the relevant laws and regulations and safe operation procedures.
1-[[2-(trifluoromethyl)phenyl]methyl]piperazine has a wide range of applications in the field of medicine. It can be used as a raw material for antidepressants, antipsychotics and anxiolytics. It has also been used in research as an agonist of serotonin and dopamine receptors.
1-[[2-(trifluoromethyl)phenyl]methyl]piperazine has many preparation methods. A common method of preparation is by reacting piperazine with 2-bromobenzonitrile and then with trifluoromethylbenzyl bromide in the presence of sodium bicarbonate to give the desired product.
Regarding safety information, 1-[[2-(trifluoromethyl)phenyl]methyl]piperazine is a chemical and requires caution. It may have irritating and corrosive effects on the eyes, skin and respiratory tract. Pay attention to personal protective measures, such as wearing protective glasses, gloves and protective mask. At the same time, contact with the skin and inhalation of its dust or vapor should be avoided. In case of accidental contact, flush with water immediately and seek medical help. In addition, it is also an environmental pollutant and should be avoided to cause pollution to the environment. In the use and storage, should comply with the relevant laws and regulations and safe operation procedures.
Last Update：2024-04-09 21:11:58
